Tab. 1.
Clinical and biochemical characteristics of patients, CSA, MTNF and TCNS results. Group I – diabetic patients with peripheral neuropathy, Group II – diabetic patients without peripheral neuropathy, Group III – non-diabetic subjects
| Clinical and biochemical characteristics | Group I (N = 75) |
Group II (N = 58) |
Group III (N = 75) |
|---|---|---|---|
| Age in years (Mean +/− SD) Range |
59.30 +/− 12.11 (40–89) |
46.98 +/− 6.82 (33–60) |
39.54 +/− 10.12 (23–72) |
| Duration of diabetes in years (Mean +/− SD) Range |
13.98 +/− 7.06 (5–38) |
7.53 +/− 4.26 (1–19) |
− |
| Male : Female | 46 : 29 | 32 : 26 | 44 : 31 |
| Weight in kg (mean +/− SD) Range |
78.52 +/− 9.60 (53–96) |
63.24 +/− 9.89 (40–80) |
63.34 +/− 10.33 (40–85) |
| Systolic blood pressure in mmHg (mean +/− SD) Range |
138.48 +/− 10.37 (110–160) |
121.48 +/− 9.58 (100–146) |
120.77 +/− 9.34 (100–140) |
| Diastolic blood pressure in mmHg (mean +/− SD) Range |
83.46 +/− 6.54 (68–94) |
76.68 +/− 6.19 (64–90) |
76.26 +/− 6.09 (60–86) |
| HbA1c levels in % (mean +/− SD) Range |
7.84 +/− 1.20 (6.10–12.50) |
5.92 +/− 0.69 (5.0–7.30) |
5.23 +/− 0.23 (5.0–5.92) |
| CSA of the tibial nerve in mm2 (mean +/− SD) Range |
22.63 +/− 2.66 (18.5–29) |
14.40 +/− 1.72 (12–18.5) |
12.42 +/− 1.10 (10–14) |
| MTNF of the tibial nerve in mm (mean +/− SD) Range |
0.47 +/− 0.09 (0.30–0.70) |
0.23 +/− 0.06 (0.10–0.40) |
0.20 +/− 0.05 (0.10–0.30) |
| TCNS (mean +/− SD) Range |
10.14 +/− 3.45 (6.0–18.5) |
1.67 +/− 1.61 (0–5) |
− |
CSA – cross sectional area; DN – diabetic neuropathy; HRUS – high resolution ultrasonography; MTNF – maximum thickness of nerve fascicles; MRI – magnetic resonance imaging; NCS – nerve conduction study; r – Pearson correlation coefficient value; TCNS – Toronto Clinical Neuropathy score; US – ultrasonography