Table 1.
Clinical characteristics and concentrations of prostaglandins (PGE2 and PGF2α) in the umbilical cord for each study group
| Term delivery without labor (n=20) | Term delivery with labor (n=20) | p value* | sPTD without funisitis (n=20) | sPTD with funisitis (n=20) | p value§ | p value† | |
|---|---|---|---|---|---|---|---|
| Maternal age (years) | 25.5 (20–35) | 26.0 (17–35) | 0.8 | 25.5 (20–36) | 23.0 (16–39) | 0.7 | 0.4 |
| Nulliparity | 10% (2/20) | 20% (4/20) | 0.7 | 10% (2/20) | 30% (6/20) | 0.2 | 0.5 |
| GA at delivery (weeks) | 39.0 (37.1–40.1) | 39.1 (37.1–40.4) | 0.9 | 31.8 (27–34) | 32.3 (28.6–34) | 0.9 | < 0.001 |
| Birth weight (gm) | 3323 (2545–4485) | 3258 (2550–3695) | 0.5 | 1818 (881–2690) | 1665 (1010–2335) | 0.6 | < 0.001 |
| Male gender | 70% (14/20) | 55% (11/20) | 0.3 | 45% (9/20) | 50% (10/20) | 0.8 | 0.8 |
| PGE2 | 133.7 (44.8–252.4) | 116.1 (33.5–354.9) | 0.9 | 87.4 (6.1–258.6) | 233.7 (61.3–1000) | 0.001 | 0.03 |
| PGF2α | 8.4 (4.1–15.2) | 8.1 (4.2–14.8) | 0.7 | 7.1 (0.6–13.1) | 9.6 (4.3–43.8) | 0.051 | 0.3 |
Data are presented as median (interquartile range) and percentage with (n);
sPTD: spontaneous preterm delivery;
PGE2 and PGF2α concentrations were expressed by pg/μg of total protein.
GA: gestational age
*
comparison between term delivery without labor and term delivery with labor
§
comparison between sPTD without funisitis and sPTD with funisitis
†
comparison between TIL and sPTD with funisitis