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. Author manuscript; available in PMC: 2019 Jan 1.

Published in final edited form as: Respir Investig. 2017 Dec 6;56(1):28–33. doi: 10.1016/j.resinv.2017.11.002

Table 2.

Multiple comparisons of CBMN endpoints, split by smoking intensity

	Lung Cancer			COPD			Healthy Controls
Micronuclei (BN- MN)	N	Mean	Std Error	N	Mean	Std Error	N	Mean	Std Error
Overall	448	3.53	(0.045)	200	1.91	(0.060)	590	1.78	(0.035)	P_trend< 0.001
Light	99	3.52	(0.093)	63	1.95	(0.112)	289	1.72	(0.051)
Moderate	106	3.55	(0.100)	50	1.88	(0.133)	143	1.83	(0.069)
Heavy	243	3.53	(0.059)	87	1.92	(0.086)	158	1.81	(0.072)
	P = 0.969			P = 0.904			P = 0.371
Bridges (BN- NPB)	N	Mean	Std Error	N	Mean	Std Error	N	Mean	Std Error
Overall	448	4.26	(0.035)	200	1.03	(0.039)	590	0.97	(0.025)	P_trend < 0.001
Light	99	4.36	(0.752)	63	1.05	(0.694)	289	0.99	(0.035)
Moderate	106	4.22	(0.746)	50	1.00	(0.857)	143	1.01	(0.053)
Heavy	243	4.24	(0.049)	87	1.06	(0.061)	158	0.90	(0.048)
	P = 0.315			P = 0.819			P = 0.255
Buds (BN- NBUDS)	N	Mean	Std Error	N	Mean	Std Error	N	Mean	Std Error
Overall	448	0.59	(0.043)	200	0.38	(0.034)	590	0.30	(0.019)	P_trend < 0.001
Light	99	0.55	(0.071)	63	0.35	(0.061)	289	0.34	(0.028)
Moderate	106	0.68	(0.069)	50	0.36	(0.069)	143	0.29	(0.038)
Heavy	243	0.56	(0.044)	87	0.42	(0.056)	158	0.26	(0.036)
	P = 0.251			P = 0.669			P = 0.216