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. Author manuscript; available in PMC: 2018 Jan 16.
Published in final edited form as: Nat Cell Biol. 2015 May 18;17(6):816–826. doi: 10.1038/ncb3169

Figure 4. TGFβ signaling induces fibronectin upregulation and macrophage recruitment to the liver pre-metastatic niche.

Figure 4

Immunofluorescence quantification of FN and αSMA expression in arbitrary units (A.U.) and F4/80+ cells in livers of mice educated with PBS (CTL), PAN02 exosomes alone (Exo), or in combination with the TGFβ receptor inhibitor A83-01 (Exo+A83-01); n = 4 (CTL) and n = 7 (Exo and Exo+A83-01) mice pooled from two experiments. The data are represented as mean±s.e.m. ***P < 0.001, N.S. stands for not significant by ANOVA. Scale bars, 200μm.