Table 2. Multivariate linear regression coefficients between cardiovascular risk factors and cognitive test scores.
| CVLTe | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FDSa | BDSb | FCBc | BCBd | Short-term recall | Delayed recall | |||||||
| B (p) | B (p) | B (p) | B (p) | B (p) | B (p) | |||||||
| Age | –0.026 (0.012)* | –0.006 (0.705) | 0.002 (0.913) | –0.002 (0.929) | –0.103 (0.010)* | –0.144 (< 0.001)* | ||||||
| Education | 0.021 (0.287) | 0.082 (0.002)* | 0.095 (0.003)* | 0.070 (0.016)* | 0.026 (0.722) | 0.061 (0.400) | ||||||
| Glucose | 0.002 (0.633) | –0.006 (0.325) | –0.005 (0.514) | 0.003 (0.663) | –0.001 (0.960) | 0.009 (0.599) | ||||||
| Total cholesterol | –0.058 (0.705) | –0.109 (0.615) | 0.252 (0.343) | 0.225 (0.357) | 1.027 (0.075) | 0.896 (0.125) | ||||||
| HDL cholesterol | 0.058 (0.705) | 0.106 (0.627) | –0.243 (0.359) | –0.215 (0.380) | –1.044 (0.071) | –0.027 (0.058) | ||||||
| LDL cholesterol | 0.057 (0.711) | 0.103 (0.636) | –0.260 (0.327) | –0.231 (0.345) | –1.018 (0.077) | –0.898 (0.124) | ||||||
| VLDL cholesterol | –0.021 (0.029)* | –0.028 (0.038)* | 0.229 (0.400) | 0.190 (0.451) | 1.061 (0.074) | 0.893 (0.137) | ||||||
| Triglycerides | –0.008 (0.003)* | –0.008 (0.031)* | –0.095 (0.375) | –0.082 (0.410) | –0.417 (0.075) | –0.350 (0.138) | ||||||
| BMIf | 0.003 (0.896) | 0.053 (0.082) | –0.033 (0.364) | –0.024 (0.487) | 0.011 (0.887) | –0.188 (0.033)* | ||||||
| Smoking history | –0.137 (0.662) | 0.009 (0.891) | –0.014 (0.968) | –0.225 (0.807) | 1.035 (0.209) | 0.367 (0.659) | ||||||
| Diabetes mellitus | –0.086 (0.852) | –0.072 (0.895) | –0.367 (0.476) | –0.473 (0.726) | –0.157 (0.896) | –0.505 (0.679) | ||||||
| Hypertension | –0.062 (0.809) | 0.046 (0.880) | 0.184 (0.521) | –1.230 (0.107) | –0.827 (0.219) | –0.535 (0.432) | ||||||
| R2 0.139 | p 0.002 | R2 0.128 | p 0.005 | R2 0.089 | p 0.003 | R2 0.059 | p 0.016 | R2 0.117 | p 0.071 | R2 0.153 | p < 0.001 | |
| Phonemic category fluency | Semantic category fluency | |||||||||||
| F | A | S | Animals | Fruits | Instruments | |||||||
| B (p) | B (p) | B (p) | B (p) | B (p) | B (p) | |||||||
| Age | –0.017 (0.715) | 0.026 (0.526) | 0.036 (0.415) | –0.064 (0.214) | –0.073 (0.040)* | –0.020 (0.604) | ||||||
| Education | 0.371 (< 0.001)* | 0.351 (< 0.001)* | 0.322 (<0.001)* | 0.399 (< 0.001)* | 0.085 (0.191) | 0.227 (0.001)* | ||||||
| Glucose | –0.004 (0.819) | –0.001 (0.945) | 0.005 (0.779) | –0.012 (0.580) | –0.017 (0.279) | 0.003 (0.832) | ||||||
| Total cholesterol | 0.246 (0.705) | –0.369 (0.523) | –0.076 (0.903) | 0.730 (0.307) | –0.104 (0.025)* | 0.644 (0.235) | ||||||
| HDL cholesterol | –0.234 (0.719) | 0.388 (0.502) | 0.096 (0.876) | –0.740 (0.301) | 0.085 (0.017)* | –0.664 (0.221) | ||||||
| LDL cholesterol | –0.251 (0.699) | 0.349 (0.545) | 0.063 (0.919) | –0.725 (0.310) | –0.115 (0.020)* | –0.647 (0.232) | ||||||
| VLDL cholesterol | 0.204 (0.760) | –0.445 (0.454) | –0.055 (0.014)* | 0.726 (0.324) | 0.124 (0.814) | 0.658 (0.238) | ||||||
| Triglycerides | –0.097 (0.712) | 0.158 (0.499) | 0.045 (0.857) | –0.294 (0.309) | –0.021 (0.025)* | –0.255 (0.244) | ||||||
| BMIg | 0.152 (0.091) | 0.089 (0.261) | 0.053 (0.542) | –0.227 (0.021)* | 0.770 (0.275) | –0.188 (0.009)* | ||||||
| Smoking history | 0.225 (0.827) | 0.556 (0.496) | 1.293 (0.148) | –0.703 (0.480) | –0.417 (0.525) | 0.272 (0.710) | ||||||
| Diabetes mellitus | –1.650 (0.706) | –1.650 (0.171) | –0.508 (0.697) | –1.517 (0.300) | 0.101 (0.964) | 0.609 (0.571) | ||||||
| Hypertension | –0.148 (0.104) | –0.148 (0.825) | –0.512 (0.481) | 0.130 (0.873) | –0.812 (0.173) | –1.021 (0.090) | ||||||
| R2 0.204 | p < 0.001 | R2 0.210 | p < 0.001 | R2 0.192 | p < 0.001 | R2 0.207 | P < 0.001 | R2 0.098 | p 0.083 | R2 0.170 | P 0.027 | |
a
Forward Digit Span;
b
Backward Digit Span;
c
Forward Corsi Block;
d
Backward Corsi Block;
e
California Verbal Learning Test;
f
Body Mass Index.
*
indicates significant association (p < 0.05).