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Mean (SE) insulin dose (A), HbA1c (B), fasting plasma glucose (C), and seven-point SMPG time profiles (D). Data for (A) is from the safety population, for (B–D), the ITT population. For (A), baseline is defined as the mean of daily doses available in the week before the first injection of SAR-Lis or Ly-Lis. ITT, intent-to-treat; Ly-Lis, Humalog® insulin lispro; SAR-Lis, SAR342434 insulin lispro; SE, standard error; SMPG, self-monitored plasma glucose.
