FIG. 1.

Mosquito-transmitted virus control strategies target multiple stages of viral transmission: vaccination of human host, suppression of mosquito population (SIT—insecticides and transgenesis), and vector competency. Several strains of the intracellular bacteria Wolbachia suppress viral growth in mosquitos, blocking their competency to transmit several arboviruses, including DENV and more recently ZIKV. Orange indicates virus-infected mosquito or human. DENV, dengue virus; SIT, sterile insect technique; ZIKV, Zika virus.