FIG. 4.

BM-MNC seeding of electrospun TEVG modulated host inflammatory cell infiltration and phenotype. F4/80 staining of seeded (A) and unseeded (B) electrospun TEVGs. Phenotypic characterization of TEVG macrophages demonstrated iNOS⁺ (Seeded: C; Unseeded: E) and CD206⁺ (Seeded: [D]; Unseeded: [F]) cells. F4/80⁺ cells in the seeded vs. unseeded group at 6 months (G); seeded group revealed significantly less macrophage infiltration (*p < 0.05). iNOS⁺ and CD206⁺ cells in the seeded versus unseeded group at 6 months (H); unseeded group showed significantly less CD206⁺ cells (****p < 0.0001). Scale bar = 20 μm. Color images available online at www.liebertpub.com/tea