Table 3.
Positive and Negative Predictive Values Based on Different Specificities and Sensitivities when the Incidence of Thyroid Storm Is Estimated as 1 per 500 (0.2%) Among Patients with Thyrotoxicosis
| Thyrotoxicosis | ||||||
|---|---|---|---|---|---|---|
| TS | Non-TS | Total | ||||
| A. If both specificity and sensitivity are 80% | ||||||
| TS based on the diagnostic criteria | Yes | 16 | 2000 | 2016 | PPV | 0.79% |
| No | 4 | 8000 | 8004 | NPV | 99.95% | |
| Total | 20 | 10,000 | 10,020 | |||
| B. If specificity is 99.9% and sensitivity is 80% | ||||||
| TS based on the diagnostic criteria | Yes | 16 | 10 | 26 | PPV | 61.54% |
| No | 4 | 9990 | 9994 | NPV | 99.96% | |
| Total | 20 | 10,000 | 10,020 | |||
Bold, point of interest.
PPV, positive predictive values; NPV, negative predictive values.