Table 2.

Distribution of Genetic Alterations in Primary Thyroid Lesions

Histopathology	Lesions, n	Positive, %	BRAF, %	RAS, %	RET, %	PPARG, %
All benign	47	1 (2%)				1 (100%)
Follicular adenoma	29	1 (3%)				1 (100%)
Other benign	18	—
All malignant	68	32 (47%)	12 (37.5%)	6 (19%)	12 (37.5%)	2 (6%)
Follicular carcinoma	6	2 (33%)		2 (100%)
Papillary carcinoma	62	30 (48%)	12 (40%)	4 (13%)	12 (40%)	2 (7%)
Classical variant	27	17 (63%)	12 (71%)		5 (29%)
Follicular, encapsulated	21	6 (29%)		4 (67%)		2 (33%)
Follicular, widely invasive	3	2 (67%)			2 (100%)
Diffuse sclerosing variant	8	4 (50%)			4 (100%)
Mix classic, follicular, solid	2	1 (50%)			1 (100%)
Oncocytic variant	1	—
Total	115	33 (29%)	12 (36%)	6 (18%)	12 (36%)	3 (9%)