Table 4.
Characteristics and Adjusted Odds Ratios of Women Aged 66–69 Years and with a Charlson Comorbidity Score = 0 Diagnosed with Early-Stage Breast Cancer in SEER Regions SEER -Medicare, 2003–2009
| Treatment | ||||||||
|---|---|---|---|---|---|---|---|---|
| N | % | Mastectomy vs. BCS + RT | BCS Only vs. BCS + RT | |||||
| All | 6369 | 100.0 | AOR | 95% CI | Sig. | AOR | 95% CI | Sig. |
| Treatment | ||||||||
| BCS+Radiation | 4246 | 66.7 | ||||||
| Mastectomy | 1239 | 19.5 | ||||||
| BCS only | 884 | 13.9 | ||||||
| Year of diagnosis | ||||||||
| 2003 | 875 | 13.7 | 1.00 | — | 1.00 | — | ||
| 2004 | 908 | 14.3 | 0.90 | 0.70–1.17 | 1.11 | 0.85–1.45 | ||
| 2005 | 896 | 14.1 | 0.90 | 0.70–1.16 | 1.07 | 0.82–1.41 | ||
| 2006 | 888 | 13.9 | 0.83 | 0.64–1.08 | 1.06 | 0.81–1.40 | ||
| 2007 | 932 | 14.6 | 0.89 | 0.70–1.15 | 0.89 | 0.67–1.17 | ||
| 2008 | 961 | 15.1 | 1.27 | 1.00–1.62 | 1.02 | 0.77–1.35 | ||
| 2009 | 909 | 14.3 | 1.12 | 0.87–1.44 | 0.80 | 0.60–1.08 | ||
| Age & health | ||||||||
| PCP visits | ||||||||
| Low | 4622 | 72.6 | 1.00 | — | 1.00 | — | ||
| High | 1747 | 27.4 | 0.95 | 0.81–1.10 | 1.05 | 0.89–1.24 | ||
| Clinical prognostic factors | ||||||||
| Stage at diagnosis | ||||||||
| I | 4142 | 65.0 | 1.00 | — | 1.00 | — | ||
| II | 2227 | 35.0 | 1.91 | 1.55–2.35 | *** | 1.17 | 0.91–1.50 | |
| ER status | ||||||||
| Positive | 5055 | 79.4 | 1.00 | — | 1.00 | — | ||
| Negative | 933 | 14.7 | 1.25 | 0.98–1.60 | 1.07 | 0.80–1.42 | ||
| Borderline/unknown | 381 | 6.0 | 1.90 | 0.91–3.96 | 1.07 | 0.56–2.07 | ||
| PR status | ||||||||
| Positive | 4261 | 66.9 | 1.00 | — | 1.00 | — | ||
| Negative | 1682 | 26.4 | 1.19 | 0.98–1.45 | 0.97 | 0.77–1.22 | ||
| Borderline/unknown | 426 | 6.7 | 0.91 | 0.44–1.86 | 1.73 | 0.93–3.24 | ||
| Tumor size | ||||||||
| 0–1 cm | 2220 | 34.9 | 1.00 | — | 1.00 | — | ||
| >2 cm | 2570 | 40.4 | 1.62 | 1.36–1.94 | *** | 0.93 | 0.78–1.12 | |
| 2–5 cm | 1498 | 23.5 | 2.86 | 2.21–3.70 | *** | 1.56 | 1.15–2.10 | ** |
| >5 cm | 81 | 1.3 | 4.31 | 2.52–7.35 | *** | 1.60 | 0.78–3.29 | |
| Tumor grade | ||||||||
| Well differentiated | 1694 | 26.6 | 1.00 | — | 1.00 | — | ||
| Moderately differentiated | 2788 | 43.8 | 1.09 | 0.91–1.30 | 1.00 | 0.83–1.21 | ||
| Poorly differentiated | 1494 | 23.5 | 1.10 | 0.89–1.36 | 1.27 | 1.01–1.60 | * | |
| Undifferentiated/unknown | 393 | 6.2 | 1.37 | 1.01–1.85 | * | 1.61 | 1.18–2.18 | ** |
| Oncology care resources | ||||||||
| Mammography screening centers | ||||||||
| Low | 3386 | 53.2 | 1.00 | — | 1.00 | — | ||
| High | 2983 | 46.8 | 1.20 | 0.93–1.55 | 0.86 | 0.63–1.17 | ||
| Oncology treatment centers | ||||||||
| Low | 3656 | 57.4 | 1.00 | — | 1.00 | — | ||
| High | 2713 | 42.6 | 0.81 | 0.63–1.05 | 1.13 | 0.84–1.54 | ||
| Type of surgeon seen | ||||||||
| General only | 761 | 12.0 | 1.00 | — | 1.00 | — | ||
| Oncology only | 393 | 6.2 | 0.96 | 0.69–1.35 | 0.44 | 0.29–0.66 | *** | |
| Both | 5215 | 81.9 | 0.92 | 0.74–1.14 | 0.65 | 0.53–0.80 | *** | |
| Socio-demographic characteristics | ||||||||
| Race | ||||||||
| White | 5786 | 90.9 | 1.00 | — | 1.00 | — | ||
| Other | 583 | 9.2 | 1.22 | 0.98–1.53 | 1.30 | 1.02–1.67 | * | |
| Education | ||||||||
| <15% college degree | 1699 | 26.7 | 1.00 | — | 1.00 | — | ||
| ≥15% college degree | 4670 | 73.3 | 0.85 | 0.71–1.01 | 0.90 | 0.74–1.09 | ||
| Annual income | ||||||||
| ≤$35,000 | 1295 | 20.3 | 1.00 | — | 1.00 | — | ||
| >$35,000 | 5074 | 79.7 | 0.78 | 0.65–0.95 | * | 0.65 | 0.53–0.80 | *** |
| Metro status | ||||||||
| Nonmetro | 1115 | 17.5 | 1.00 | — | 1.00 | — | ||
| Metro | 5254 | 82.5 | 0.79 | 0.64–0.96 | * | 0.79 | 0.63–0.98 | * |
*
p < 0.05.
**
p < 0.01.
***
p < 0.001.