. Author manuscript; available in PMC: 2018 Jan 16.

Published in final edited form as: Nat Rev Nephrol. 2017 Nov 27;14(1):57–70. doi: 10.1038/nrneph.2017.155

Table 2.

Consequences of dyslipidaemia in nephrotic syndrome or CKD

Complications associated with dyslipidaemia in nephrotic syndrome	Estimates of individual and additive risk for complications occurring in different disease states
	Nephrotic syndrome	CKD	Nephrotic syndrome and CKD
Cardiovascular disease
Atherosclerosis	++	+	+++
Myocardial infarction	++	+	+++
Cerebrovascular accident (stroke)	++	+	+++
Progressive kidney disease
Glomerulosclerosis	++	+	+++
• Mesangial cell proliferation	+	±	+
• Podocyte injury	+	+	++
Tubulointerstitial disease	++	+	+++
• Proximal tubular cell injury	+	+	++
Other
Thromboembolism	++	±	++

±, minimal risk; +, low risk; ++, moderate risk; +++, high risk; CKD, chronic kidney disease.