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Series of Monte Carlo studies for the simulation – I setting, each simulation with larger cohorts.
| Approach | Bias (SD) from N = 100 cohorts | |||
|---|---|---|---|---|
|
| ||||
| Cohort size (n) | n = 5,000 | n = 10,000 | n = 50,000 | n = 100,000 |
|
|
||||
| MSCM | 0.013 (0.150) | 0.007 (0.107) | 0.011 (0.049) | 0.003 (0.033) |
| Modified Sequential Cox | 0.011 (0.157) | 0.003 (0.100) | 0.004 (0.048) | −0.001 (0.037) |
