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. 2018 Jan 1;25(1):16–26. doi: 10.5551/jat.RV17010

Fig. 4.

Fig. 4.

Modulation of the functions of sphingosine 1-phosphate by apoM

Apolipoprotein M (ApoM) strengthens the agonist properties of sphingosine 1-phosphate (S1P) for S1P1 (anti-atherosclerotic S1P receptor), while it weakens the agonist properties for S1P2 (proatherosclerotic S1P receptor).