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. Author manuscript; available in PMC: 2018 Nov 28.
Published in final edited form as: ACS Nano. 2017 Oct 18;11(11):11584–11593. doi: 10.1021/acsnano.7b06524

Figure 4.

Figure 4

Backfilling with shorter PEGs does not affect the level of skin deposition. EPC liposomes were formulated with EPC/DSPE-PEG-2000 and either DSPE-PEG-350 or DSPE-PEG-700 as described in the Methods). (A) Whole skin pieces (approximately 4 cm × 3 cm) were collected post-mortem and scanned with Li-COR Odyssey at 800 nm (DiR) and 700 nm (skin autofluorescence). Representative images are shown. All groups showed accumulation of DiR, regardless of the PEG size. (B) Mean fluorescence intensity quantification showed no difference between experimental groups (p value 0.22; n = 3, two tailed unpaired t test).