Location of the PURA gene in relation to other genes and markers that have been mapped to band region 5q31. The order of the markers shown is adopted from bacmaps at the LBNL Human Genome Center. Other genes mapped to chromosome 5 band region q31 encode proteins that include: interferon regulatory factor 1, IRF1; interleukin-9, IL-9; a CDC2 phosphatase, CDC25C; early growth response-1 zinc-finger protein, EGR-1; myelomonocytic differentiation antigen, CD14; and a histone deacetylase, HDAC3. (Figure from
Lezon-Geyda et al., 2001, Leukemia, 15:6, 954–962 used with permission.)