Table 3.

Classification of problems/imperfections for T1.

Problem code

Imperfection code

0 = No problem 1 = Multiple/Unknown problems 2 = Missing or incomplete modality 3 = Bad FOV 4 = Bad registration: Bad head motion/Noise 5 = Bad registration: Structurally atypical: Important lesions 6 = Bad registration: Structurally atypical: Big Ventricles 7 = Bad registration: General Registration failure 8 = Bad registration: Bad brain mask on the top 9 = Bad registration: Bad brain mask on the temporal lobe 10 = Bad registration: Brain mask out of the brain

1 = Multiple/Unknown imperfections 2 = Bad head movement 3 = Movement-related ringing/blurring 4 = Bias field/contrast problem 5 = Structurally atypical 6 = Problem on top (brain mask) 7 = Problem on temp. lobe (brain mask)

Incomplete = The expected number of images or any of the dimensions (including the temporal dimension) is incorrect.

Structurally atypical: The subject is anatomically atypical. This may be due to a pathology although there was no clinical assessment to confirm this. The problem may be so severe that registration is strongly affected (and thus, the image is deemed unusable for the automated processing pipeline).