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. 2018 Jan 12;8:376. doi: 10.3389/fendo.2017.00376

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Copyright © 2018 Kristensen, Mamsen, Jeppesen, Bøtkjær, Pors, Borgbo, Ernst, Macklon and Andersen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Granulosa cell expression of selected genes in human small antral follicles. Graphs show relative expression levels of FSHR, CYP19a1, AR, and AMH in relation to follicular diameter. Values are presented as mean ± SEM. Statistically significant differences were observed in the mRNA expression levels of FSHR [analysis of variance (ANOVA); N = 315; P < 0.002] and AR (ANOVA; N = 316; P < 0.03), but not for CYP19a1 (ANOVA; N = 252; P > 0.10) and AMH (ANOVA; N = 277; P > 0.10). Specific numbers for the analyzed follicle groups divided according to follicular diameter are shown in Table S3 in Supplementary Material.