Table 2.
PedsQL scale scores and differences between young adults with bleeding disorders and the PedsQL norm groups
| PedsQL (sub)scale | Bleeding disorders | Healthy peers | Chronic ill peersa | Bleeding disorders versus healthy | Bleeding disorders versus chronic ill | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | Median (range) | Mean (SD) | N | Median (range) | Mean (SD) | N | Median (range) | Mean (SD) | p Value | Effect size r | p Value | Effect size r | |
| Men | |||||||||||||
| Total score | 78 | 84.78 (60–100) | 83.65 (11.85) | 267 | 90.22 (33–100) | 87.51 (11.88) | 50 | 86.96 (37–100) | 82.48 (13.30) | 0.00* | 0.14 | 0.73 | 0.05 |
| Physical health | 78 | 90.63 (37–100) | 86.18 (15.99) | 267 | 96.88 (0–100) | 91.50 (12.82) | 50 | 93.75 (37–100) | 87.13 (14.69) | 0.00* | 0.16 | 0.89 | 0.03 |
| Emotional functioning | 78 | 80.00 (25–100) | 81.09 (16.65) | 267 | 85.00 (15–100) | 82.36 (17.25) | 50 | 82.50 (20–100) | 78.80 (18.17) | 0.44 | 0.03 | 0.55 | 0.07 |
| Social functioning | 78 | 90.00 (45–100) | 86.41 (13.79) | 267 | 95.00 (20–100) | 89.46 (13.28) | 50 | 90.00 (35–100) | 84.20 (17.45) | 0.06 | 0.10 | 0.59 | 0.07 |
| School/work functioning | 78 | 80.00 (35–100) | 79.42 (15.46) | 267 | 85.00 (20–100) | 84.33 (14.81) | 50 | 80.00 (30–100) | 77.00 (16.48) | 0.01* | 0.14 | 0.57 | 0.08 |
| Psychosocial health | 78 | 81.67 (47–100) | 82.31 (13.03) | 267 | 88.33 (28–100) | 85.38 (13.37) | 50 | 83.33 (37–100) | 80.00 (14.44) | 0.03 | 0.10 | 0.43 | 0.08 |
| Women | |||||||||||||
| Total score | 17 | 80.43 (49–100) | 78.64 (13.15) | 245 | 84.78 (52–100) | 84.10 (10.70) | 87 | 75.00 (24–100) | 73.30 (16.40) | 0.09 | 0.12 | 0.22 | 0.12 |
| Physical health | 17 | 87.50 (38–100) | 80.88 (16.75) | 245 | 90.63 (16–100) | 87.53 (12.89) | 87 | 78.13 (9–100) | 72.59 (23.57) | 0.07 | 0.12 | 0.28 | 0.14 |
| Emotional functioning | 17 | 65.00 (45–100) | 69.41 (16.29) | 245 | 75.00 (25–100) | 74.39 (17.05) | 87 | 70.00 (10–100) | 68.56 (18.33) | 0.17 | 0.07 | 0.74 | 0.02 |
| Social functioning | 17 | 90.00 (50–100) | 86.18 (86.18) | 245 | 90.00 (40–100) | 88.04 (13.31) | 87 | 80.00 (20–100) | 79.43 (16.77) | 0.73 | 0.03 | 0.08 | 0.15 |
| School/work functioning | 17 | 80.00 (45–100) | 76.76 (16.48) | 245 | 85.00 (20–100) | 84.39 (13.97) | 87 | 75.00 (20–100) | 73.05 (18.70) | 0.05 | 0.13 | 0.46 | 0.08 |
| Psychosocial health | 17 | 78.33 (55–100) | 77.45 (12.32) | 245 | 83.33 (52–100) | 82.27 (11.93) | 87 | 76.67 (25–100) | 73.68 (15.53) | 0.12 | 0.10 | 0.37 | 0.09 |
Higher scores indicate better HRQOL
N number, M mean, SD standard deviation
* Difference at p < 0.008, adjusted for multiple testing
a Most common conditions chronically ill sample were: asthma (34.3%), psychiatry (10.9%), gastro enterology (10.2%), and skin disease (5.8%)