Table 1.
Effect of methanolic extract of Cola nitida on body weight, food intake and water intake in male Wistar rats
| GROUPS | CONTROL | FRD | MECN1 | MECN2 | MECN3 | MECN4 | MECN5 | MECN6 |
|---|---|---|---|---|---|---|---|---|
| Weight change (g/week) | 10.2±1.5 | 3.5±1.2* | 4.8±0.5* | 2.0±1.4* | 4.0±0.7* | 4.5±0.8* | 4.6±1.0* | 4.3±0.8* |
| Food intake (g/day) | ||||||||
| W0 | 10.5±3.0 | 11.1±1.3 | 9.6±1.0 | 10.7±1.2 | 12.3±1.1 | 11.1±0.8 | 13.2±0.2 | 10.9±0.5 |
| ΔW1 | 0.4±0.9 | 2.0±1.1 | 0.5±0.9 | 3.0±1.2 | 0.7±0.8 | 1.1±0.6 | 1.4±1.1 | 0.9±0.5 |
| ΔW2 | 0.5±0.1 | 1.4±1.3 | 0.7±0.7 | 3.3±1.7 | 1.5±0.8 | 1.5±0.7 | 1.2±0.9 | 0.4±0.8 |
| Water intake (ml/day) | ||||||||
| W0 | 15.6±8.0 | 14.8±5.7 | 16.0±3.7 | 16.8±3.0 | 17.6±3.4 | 15.7±3.3 | 16.1±4.2 | 17.6±10.7 |
| ΔW1 | 5.0±0.8 | 6.8±0.8 | 0.5±0.6*,# | 2.8±0.7# | 3.8±0.7# | 2.0±0.6*,# | 7.2±0.9 | 4.0±1.1 |
| ΔW2 | 6.1±0.6 | 7.9±0.9 | 0.3±1.0*,# | 2.8±0.9*,# | 11.0±0.5*,# | 9.8±0.5* | 3.7±0.6# | 9.6±0.5* |
Data are expressed as mean ± S.E.M. n=6. Data were analyzed by one-way ANOVA followed by Bonferroni post hoc test.
*
p<0.05 vs Control;
#
p<0.05 vs FRD.
ΔW1 (change in week 1); ΔW2 (change in week 2).