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C. dubliniensis induces long term protection against polymicrobial IAI. Mice (n = 10/group) were injected i.p. with C. dubliniensis and S. aureus as the primary challenge 14, 30, and 60 days prior to rechallenge with C. albicans / S. aureus (standard inocula). Animals receiving no primary challenge served as the positive (lethal) control. Mice were monitored for 10 days post-rechallenge. *, significantly different from control (P < 0.05) by log rank Mantel-Cox test.
