Table I.
Clinicopathological characteristics of high TSPAN1 expression in 60 patients with esophageal carcinoma.
| Groups | Patients, n (%) | TSPAN1 high expression, n (%) | χ2 | P-value |
|---|---|---|---|---|
| Gender | ||||
| Male | 50 (83.33) | 43 (86.00) | 0.235 | 0.628 |
| Female | 10 (16.67) | 8 (80.00) | ||
| Age, years | ||||
| ≤60 | 23 (38.33) | 18 (78.26) | 1.329 | 0.249 |
| >60 | 37 (61.67) | 33 (89.18) | ||
| Location | ||||
| Upper esophagus | 11 (18.33) | 8 (72.72) | 1.711 | 0.425 |
| Median esophagus | 28 (46.67) | 25 (89.28) | ||
| Lower esophagus | 21 (35.00) | 18 (85.71) | ||
| Histological differentiation | ||||
| High | 18 (30.00) | 12 (66.67) | 9.020 | 0.011 |
| Moderate | 18 (30.00) | 15 (83.33) | ||
| Low | 24 (40.00) | 24 (100.00) | ||
| Depth of invasion | ||||
| T1a | 13 (21.67) | 8 (61.53) | 8.908 | 0.012 |
| T2b | 17 (28.33) | 14 (82.35) | ||
| T3c | 30 (50.00) | 29 (96.67) | ||
| Lymph node metastasis | ||||
| Positive | 36 (60.00) | 34 (94.44) | 6.296 | 0.012 |
| Negative | 24 (40.00) | 17 (70.83) | ||
| Ki-67 expression | ||||
| High | 53 (88.33) | 48 (90.57) | 11.039 | 0.001 |
| Low | 7 (11.67) | 3 (42.85) |
Depth of the tumor up to
a
mucous and submucosa
b
muscle
c
fibrous membranes and adjacent organs. TSPAN1, tetraspanin 1.