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. 2017 Dec 8;8:2406. doi: 10.3389/fmicb.2017.02406

FIGURE 4.

FIGURE 4

Anti-infective activity of L. casei BL23 was mediated by some cellular structural components irrespective of cell viability. The survival rate (A) of conventional zebrafish larvae treated with live or dead cells of L. casei BL23 at a dose of 105 CFU/ml after infected with A. veronii. The survival rate (B) of conventional zebrafish larvae treated with live or dead cells of L. casei BL23 at a dose of 106 CFU/ml after infected with A. veronii. The survival rate (C) of conventional zebrafish larvae treated with live or dead cells of L. casei BL23 at a dose of 107CFU/ml after infected with A. veronii. The survival rate (D) of GF zebrafish larvae treated with dead cells of L. casei BL23 at a dose of 105, 106, and 107 CFU/Ml, respectively after infected with A. veronii. The mRNA levels of TNF-α (E), IL-1β (F), IL-10 (G), and Saa (H) from GF and dead BL23 (106 CFU/mL) treated zebrafish at certain time points after infected with A. veronii. Asterisks indicate significant difference compared with control (∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001).