Table 1. Baseline Demographic, Cognitive, Clinical, and Thalamic Volume Scores.
|
TCT (N=22; males=14) |
CG (N=22; males=15) |
|||||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | t-Value | p-Value | |
| Age (years) | 23.28 | 4.57 | 21.25 | 3.68 | 1.62 | 0.11 |
| Duration of illness (years) | 1.68 | 1.22 | 1.71 | 1.38 | −0.09 | 0.93 |
| Education (years) | 12.73 | 1.86 | 12.55 | 3.21 | 0.22 | 0.82 |
| Verbal IQ (standard score) | 105.73 | 13.94 | 103.50 | 15.33 | 0.50 | 0.62 |
| Left thalamus (cubic ml) | 7332.05 | 971.00 | 7487.77 | 804.08 | −0.58 | 0.57 |
| Right thalamus (cubic ml) | 7460.22 | 1108.65 | 7728.18 | 902.96 | −0.88 | 0.38 |
| Neurocognition (Z-score) | −1.01 | 0.81 | −0.77 | 0.70 | −1.07 | 0.29 |
| PANSS total | 60.54 | 11.41 | 65.71 | 18.82 | −1.08 | 0.29 |
| PANSS general | 31.82 | 6.88 | 34.81 | 10.83 | −1.08 | 0.29 |
| PANSS positive | 12.05 | 3.42 | 13.24 | 4.76 | −0.94 | 0.35 |
| PANSS negative | 16.68 | 6.48 | 17.67 | 7.17 | −0.47 | 0.64 |
| Medication (CPZ equivalence) | 361.11 | 456.56 | 387.08 | 346.47 | −0.16 | 0.87 |
Abbreviations: CG, computer games; CPZ, chlorpromazine equivalents; IQ, intelligence quotient; PANSS, Positive and Negative Symptom Scale; TCT, targeted cognitive training.