Table 2.

Top 25 differentially expressed miRNAs in relation to chronological age

miRNA	Estimated Betaa	SE	R‐squared	P‐Value
miR‐99b‐5p	0.07	0.002	0.15	1.16E‐286
miR‐130b‐5p	0.06	0.002	0.11	3.04E‐227
miR‐505‐5p	0.06	0.002	0.12	3.04E‐226
miR‐425‐3p	0.08	0.002	0.10	8.58E‐203
miR‐144‐5p	0.11	0.004	0.09	1.55E‐165
miR‐182‐5p	0.10	0.003	0.08	7.29E‐157
miR‐1275	0.08	0.003	0.08	5.40E‐149
miR‐601	0.09	0.003	0.08	4.48E‐146
miR‐206	0.07	0.003	0.08	4.48E‐139
miR‐30a‐5p	0.03	0.001	0.08	9.07E‐132
miR‐218‐5p	0.07	0.003	0.07	4.94E‐130
miR‐30d‐5p	0.04	0.002	0.07	9.10E‐127
miR‐502‐3p	0.05	0.002	0.06	5.28E‐116
miR‐28‐3p	−0.08	0.003	0.06	7.96E‐114
miR‐197‐3p	0.04	0.002	0.06	3.69E‐111
miR‐320b	0.04	0.002	0.07	4.77E‐110
miR‐576‐3p	0.06	0.002	0.06	2.58E‐105
miR‐181a‐5p	0.06	0.003	0.05	2.61E‐87
miR‐18a‐5p	0.05	0.003	0.05	2.93E‐86
miR‐223‐5p	0.05	0.002	0.05	6.86E‐86
miR‐339‐5p	0.04	0.002	0.05	1.65E‐85
miR‐24‐3p	0.03	0.001	0.05	2.08E‐84
miR‐22‐3p	−0.06	0.003	0.05	2.14E‐84
miR‐345‐5p	0.04	0.002	0.05	1.66E‐82
miR‐302c‐3p	0.08	0.004	0.05	2.83E‐82

^aHigher Ct values indicate lower miRNA expression levels. Therefore, positive beta values indicate negative associations between miRNA expression and age.