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. 2017 Dec 5;7:299. doi: 10.3389/fonc.2017.00299

Table 2.

Multivariate analysis of association with time to disease recurrence.

Category Variable 95% confidence interval
HR Lower Upper p-Value
Age at diagnosis 1-year increase 1.06 0.98 1.14 0.17
Gender Male (vs. female) 34.2 0.81 1.438 0.064
ECOG 1 or 2 (vs. 0) 0.77 0.21 2.79 0.69
Smoking status Current or former smoker (vs. non-smoker) 1.68 0.53 5.35 0.38
HPV p16 Negative (vs. positive) 1.44 0.28 7.29 0.66
Not documented (vs. positive) 1.94 0.49 7.72 0.35
Negative (vs. not documented) 0.74 0.11 5.10 0.76
BMI at RT start 1-U increase 1.15 1.00 1.33 0.049
Percent BMI loss 1% greater loss 0.85 0.73 1.00 0.045
PEG timing Placed prior to treatment initiation (vs. no) 9.85 1.58 60.6 0.014
Placed during treatment (vs. no) 0.43 0.09 2.11 0.30

HR, hazard ratio; RT, radiation therapy; PEG, percutaneous endoscopic gastrostomy tube.