Table 3.

Multivariate analysis of association with time to death.

Category	Variable		95% confidence interval
		HR	Lower	Upper	p-Value
Age at diagnosis	1-year increase	1.09	1.00	1.18	0.044
Gender	Male (vs. female)	13.21	0.55	315.6	0.11
ECOG	1 or 2 (vs. 0)	0.98	0.26	3.66	0.97
Smoking status	Current or former smoker (vs. non-smoker)	0.86	0.26	2.87	0.81
HPV p16	Negative (vs. positive)	1.77	0.28	11.28	0.55
	Not documented (vs. positive)	3.36	0.84	13.43	0.087
	Negative (vs. not documented)	0.53	0.07	4.02	0.54
BMI at RT start	1-U increase	1.20	1.04	1.38	0.012
Percent BMI loss	1% greater loss	0.78	0.66	0.93	0.0054
PEG timing	Placed prior to treatment initiation (vs. no)	11.62	1.77	76.47	0.011
	Placed during treatment (vs. no)	0.43	0.08	2.24	0.32

HR, hazard ratio; RT, radiation therapy; PEG, percutaneous endoscopic gastrostomy tube.