Table 4.

Summary of quality and outcome measures of selected RCTs in reviews Calamita et al, Penagos et al and added Pham-Thi et al ^{29 32 44}

Review	RCT	Eligible	Jadad score				Reported on asthma symptoms	Reported on exacerbations	Reported on asthma control	Reported on disease-specific quality of life	Reported on lung function (FEV1)
			Randomisation*	Blinding†	Withdrawals‡	Total
Calamita29	Bahceciler et al 54	Yes	1	1	1	3	+	–	–	–	–
	Hirsch et al 55	Yes	2	1	1	4	+	–	–	–	–
	Niu et al 24	No, conference abstract
	Novembre et al 56	No, Italian language
	Pajno et al 57	Yes	2	1	1	4	+	–	–	–	–
	Pajno et al 58§	Yes	2	1	1	4	–	–	–	–	+
	Rodriguez Santos et al 59	No, Spanish language
	Rolinck-Werninghaus et al 60	Yes	1	2	0	3	+	–	–	–	–
	Yuksel et al 61	No, Spanish language
Penagos32	Bahceciler et al 54	Overlap with Calamita
	Caffarelli et al 62	No, children with asthma not separately analysed
	Hirsch et al 55	Overlap with Calamita
	Ippoliti et al 63	Yes	1	1	0	2	+	–	–	–	+
	Niu et al 64	Yes	1	1	1	3	+	–	–	–	+
	Pajno et al 65	Yes	2	1	0	3	+	–	–	–	–
	Rolinck-Werninghaus et al 60	Overlap with Calamita
	Tari et al 66	No, Spanish language
	Vourdas et al 67	No, children with asthma not separately analysed
Pham-Thi44		Yes	2	1	1	4	+			+	+
Total							8	0	0	1	4

*1 point if randomisation is mentioned; 1 additional point if the method of randomisation is appropriate; −1 point if the method of randomization is inappropriate.

†1 point if blinding is mentioned; 1 additional point if the method of blinding is appropriate; −1 point if the method of blinding is inappropriate.

‡1 point if the number and the reasons for withdrawal in each group are stated.

§Same patients as Pajno et al ⁵⁷. 

FEV₁, forced expiratory volume in 1 s; RCT, randomised controlled trial.