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Effect of IFN-γ on production of anti-SINV IgG subclasses in the brain. Anti-SINV IgG1 (a), IgG2a (b), IgG2b (c) and IgG3 (d) were measured in brains of WT B6, Ifngr1−/− and Ifng−/− mouse brains by EIA. Data are presented as mean ODs±sem for three to four mice per strain per time point; *P<0.05, **P<0.01, ****P<0.0001, WT B6 vs Ifngr1−/−; #P<0.05, ##P<0.01, ###P<0.001, ####P<0.0001, WT B6 vs Ifng−/−; †P<0.05, Ifngr1−/− vs Ifng−/−, Tukey’s multiple comparisons test.
