TEM analysis of disaggregation of HttEx1Q
48 fibrils. On the left: HttExon1Q
48 fibrils 24 h post‐PreSP treatment (
t = 0 h; same image as depicted in Figs
1D and G, and
2C); middle: HttExon1Q
48 fibrils at
t = 20 h; right: disaggregation of HttExon1Q
48 fibrils by nematode chaperones (HSP‐1, HSP‐110, DNJ‐13, ATP)
t = 20 h. A scheme of the experimental outline is depicted below. Scale bars: 100 nm.