Table 2.
Ranked list of the 300 tumor suppressor genes on mouse chromosomes 9, 10, 12, and 14 after being mapped from the human chromosomes, preserving their original CHROM rank. Loss of smaller ranked TSGs contributed most to tumorigenesis in the human tumors
| Gene name | Mouse chromosome | Potency rank |
|---|---|---|
| DNMT3A | 12 | 60 |
| ZFP36L1 | 12 | 74 |
| FANCM | 12 | 116 |
| FOXA1 | 12 | 118 |
| TRAF3 | 12 | 128 |
| ARHGAP5 | 12 | 153 |
| ASXL2 | 12 | 158 |
| NEK9 | 12 | 183 |
| BTBD7 | 12 | 219 |
| DAAM1 | 12 | 236 |
| MOAP1 | 12 | 244 |
| YLPM1 | 12 | 274 |
| PBRM1 | 14 | 6 |
| Rb1 | 14 | 7 |
| BAP1 | 14 | 33 |
| Zc3h13 | 14 | 36 |
| AJUBA | 14 | 77 |
| CHD8 | 14 | 87 |
| Sox21 | 14 | 131 |
| Dach1 | 14 | 143 |
| DENND6A | 14 | 154 |
| Rbm26 | 14 | 164 |
| SPCS1 | 14 | 208 |
| NFATC4 | 14 | 225 |
| TTC18 | 14 | 227 |
| PPP3CC | 14 | 261 |
| Kbtbd7 | 14 | 263 |
| SETD2 | 9 | 15 |
| ATM | 9 | 25 |
| TGFBR2 | 9 | 47 |
| SMARCA4 | 9 | 51 |
| USP28 | 9 | 65 |
| KEAP1 | 9 | 82 |
| MYO6 | 9 | 91 |
| TCF12 | 9 | 101 |
| KMT2A | 9 | 102 |
| SIN3A | 9 | 130 |
| HERC1 | 9 | 142 |
| TMEM30A | 9 | 212 |
| RNF111 | 9 | 250 |
| DOPEY1 | 9 | 252 |
| ATR | 9 | 275 |
| SIK3 | 9 | 278 |
| STK11 | 10 | 38 |
| SMARCB1 | 10 | 75 |
| MBD6 | 10 | 93 |
| CCAR1 | 10 | 97 |
| JMJD1C | 10 | 114 |
| RUFY2 | 10 | 155 |
| MED23 | 10 | 157 |
| HDAC2 | 10 | 165 |
| STX7 | 10 | 167 |
| ATG5 | 10 | 195 |
| PTPRK | 10 | 203 |
| TMPO | 10 | 210 |
| GNPTAB | 10 | 221 |
| CCDC38 | 10 | 288 |