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Replication of C. burnetii strains in bovine (A) and human MDM (B) measured by TCID50 assay (left) and qPCR (right). Cells were inoculated with C. burnetii strains (100 MOI, 1 h). Numbers of viable bacteria (TCID50 assay, n = 3) and of genome equivalents (GE; qPCR, n = 6) were quantified at 1, 7, and 14 day p. i.. Results per C. burnetii strain are shown as individual curves or as box-whisker plots. Strains are indicated by numbers as listed in Table 1.
