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. 2017 Dec 19;113(12):2609–2620. doi: 10.1016/j.bpj.2017.10.026

Figure 1.

Figure 1

(A) Given here is a schematic of the amino acid sequence of human HMGA2 highlighting the AT-hook domains. (B) Given here is a Western blot of HMGA2 knockdown at 48 h post transfection using an anti-Tubulin (control) and anti-HMGA2 antibody. (C) The effect of HMGA2 knockdown on cell viability was monitored for HEK293T cells at 24-h intervals over 96 h. A significant loss in viability was observed upon transfection with the HMGA2 siRNA. Data points are shown as an average of eight measurements with error bars corresponding to the SD. (D) Shown here is the Coomassie-stained SDS-PAGE of purified HMGA2. To see this figure in color, go online.