Table 1.

Summary of Hydrodynamic Parameters

Parameters	HMGA2	RF		HMGA2-RF Complex
	Experimental Analysis	Experimental Analysis	HYDROPRO DAMMIN	Experimental Analysis	HYDROPRO DAMMIN	HYDROPRO MONSA
Rh (nm)a	2.58 ± 0.25	4.12 ± 0.24	4.06 ± 0.05	4.65 ± 0.15	4.57 ± 0.04	4.37 ± 0.10
Rg (nm)b	2.45 ± 0.06	4.54 ± 0.14	4.51 ± 0.12	4.85 ± 0.06	4.88 ± 0.07	4.77 ± 0.01
Dmax (nm)b	8.0	15.4	15.7 ± 0.27	15.0	15.3 ± 0.12	15.0 ± 0.20
s020,w (S)c	1.12 ± 0.12	3.86 ± 0.12	4.03 ± 0.05	4.06 ± 0.11	4.11 ± 0.05	4.31 ± 0.10
Mwd	11.70	41.40	—	53.10	—	—
Mwe	11.80	43.03	—	55.47	—	—
Chif	—	1.2h	—	1.0h	—	—
				1.2, 1.2, 1i
NSDg	—	0.73 ± 0.08h	—	0.83 ± 0.03h	—	—
				0.87 ± 0.06i

^aExperimentally measured using DLS with errors obtained from linear regression analysis.

^bExperimentally measured using GNOM analysis from SAXS data.

^cExperimentally measured using AUC.

^dCalculated from amino acid/nucleotide sequence.

^eCalculated from R_h and s⁰_20,w.

^fGoodness-of-fit parameter suggesting agreement between raw data and data back-calculated from the ab initio model.

^gNormalized spatial discrepancy indicating agreement between individual models.

^hData from DAMMIN.

ⁱData from MONSA.