Table 2.
Concentrations of JWH-210 and/or metabolites in solid tissues and body fluids, in which they were quantifiable, including slope range and intercept range; concentrations are the mean of 6 values in ng/g including standard deviation (SD); *indicates less replicates.
| Specimen | Analyte | Mean Conc. |
Slope Range
(a)# |
Intercept Range
(b)# |
|---|---|---|---|---|
| Cerebrum | JWH-210 | 20 ± 6.8 | 0.036-0.058 | 0.55-1.17 |
| Cerebellum | JWH-210 | 32 ± 9.0 | 0.05-0.082 | 1.27-2.27 |
| Lung (right) | JWH-210 | 6.9 ± 2.1 | 0.0563-0.0751 | 0.288-0.66 |
| Lung (left) | JWH-210 | 8.6 ± 4.4 | 0.032-0.0653 | 0.164-0.923 |
| Liver | JWH-210 | 14 ± 6.2 | 0.0264-0.0704 | 0.141-1.28 |
| HO-JWH-210 | 0.67 ± 0.24* | 0.79-0.912 | 0.39-2.98 | |
| JWH-210-COOH | 4.5 ± 2.9 | 0.0347-0.0951 | 0.068-0.415 | |
| Kidney (right) | JWH-210 | 53 ± 45 | 0.0409-0.064 | 0.619-6.06 |
| Kidney (left) | JWH-210 | 43 ± 34 | 0.0312-0.056 | 0.363-3.38 |
| HO-JWH-210 | 1.0 ± 0.2* | 0.327-0.768 | 0.185-1 | |
| Bile | JWH-210 | 26 ± 19 | 0.005-0.0074 | 0.0556-0.448 |
| HO-JWH-210 | 110 ± 123 | 0.0108-1.05 | 0.0398-4.07 | |
| Heart | JWH-210 | 19 ± 6.1 | 0.0489-0.0692 | 0.50-1.64 |
| Spleen | JWH-210 | 11 ± 6.8 | 0.0392-0.0596 | 0.159-0.93 |
| HO-JWH-210 | 1.6 ± 0.49* | 0.2175-0.3275 | 0.2449-0.7294 | |
|
Skeletal Muscle |
JWH-210 | 21 ± 8.0 | 0.0592-0.0736 | 0.495-1.98 |
| HO-JWH-210 | 1.0 ± 0.37* | 0.271-0.333 | 0.181-0.389 | |
| Psoas | JWH-210 | 20 ± 9.5 | 0.0605-0.0729 | 0.792-2.29 |
| HO-JWH-210 | 1.8 ± 0.23* | 0.2545-0.3003 | 0.4656-0.5375 | |
| Dura | JWH-210 | 1.7 ± 0.8 | 0.0473-0.1092 | 0.0296-0.1696 |
#y = a x + b; concentration x can be calculated as minus value.