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. 2017 Jul;15(5):789–798. doi: 10.2174/1570159X14666161208153644

Table 3.

Differences between akathisia and restless leg syndrome (RLS).

Akathisia RLS
Prevalence 15-35% 3-9%
Gender prevalence Same in both male and females Tend to occur more in females
Motor restlessness Can be absent Present
Paresthesia Absent Present mostly at night and disappears in the morning
Time of occurrence Anytime Mostly at night
Sleep disturbance Absent Patient usually cannot sleep
Lying down Somewhat decreases it Aggravates it
Myoclonus Absent Present with severe cases
Treatment Anticholinergic and Beta-blockers Dopamine agonists and opiates
HHS Vulnerability Disclosure