Table 1.

Table of proteins showing the highest increase in abundance in young (n = 7) and old (n = 6) tenocyte-derived constructs, according to fold change

Highest mean condition	Accession (human)	Protein description	Function	Peptide count	Fold change	ANOVA (p value)
TEC derived from old cells	O94875	Sorbin and SH3 domain containing protein 2	Actin filament organization	10	5,1	0,02
	V9HWA5	Calponin 1	Actin binding, calmodulin binding	4	3,6	0,02
	P02461	Collagen type III alpha 1	ECM Collagen	38	3,5	0,01
	O43294	Transforming growth factor beta induced protein	ECM Glycoprotein	3	3,2	0,04
	Q05707	Collagen type XIV alpha 1	ECM Collagen	3	3,0	0,02
	P08123	Collagen type I alpha 2	ECM Collagen	48	3,0	0,00
	Q8WX93	Palladin, cytoskeletal associated protein	Enzyme	20	3,0	0,02
TEC derived from young cells	Q99623	Prohibitin 2	Transcription regulator	2	3,9	0,05
	P05106	Integrin beta 3	Transmembrane receptor	2	2,8	0,01
	P11166	Solute carrier family 2 member 1	Transporter	3	2,2	0,02
	P07919	Cytochrome b-c1 complex subunit 6	Enzyme	2	2,1	0,05
	P07093	Serpin family E member 2	ECM Regulator	3	2,1	0,04
	P08648	Integrin alpha 5	Transmembrane receptor	2	2,1	0,02
	P30049	ATP synthase subunit delta, mitochondrial	Enzyme	5	2,0	0,04

Only proteins with ≥2 unique peptides and p < 0.05 were presented. Abundant proteins in each group are also highlighted in Additional file 1