Table 1.
Clinical and functional characteristics of the study patients
| Anthropometric variables | Lung cancer N = 20 | Lung cancer-COPD N = 20 |
|---|---|---|
| Age, years | 64 (12) | 65 (9) |
| Male, N/female, N | 13/7 | 20/0 |
| BMI, kg/m2 | 26 (5) | 26 (5) |
| Smoking history | ||
| Current: N, % | 12, 60 | 14, 70 |
| Ex-smoker: N, % | 5, 25 | 6, 30 |
| Never smoker: N,% | 3, 15 | 0, 0¶ |
| Pack-years | 53 (25) | 57 (20) |
| Lung function testing | ||
| vFEV1, % pred | 92 (8) | 61 (14)¶¶¶ |
| FEV1/FVC, % pred | 77 (6) | 60 (8)¶¶¶ |
| DLCO, % pred | 88 (12) | 72 (21)¶¶¶ |
| KCO, % pred | 88 (11) | 73 (17)¶¶¶ |
| TNM staging | ||
| Stage IA: N, % | 5, 25 | 5, 25 |
| Stage IB: N, % | 0, 0 | 4, 20 |
| Stage IIA: N, % | 1, 5 | 6, 30 |
| Stage IIB: N, % | 4, 20 | 2, 10 |
| Stage IIIA: N, % | 3, 15 | 3, 15 |
| Stage IIIB: N, % | 4, 20 | 0, 0 |
| Stage IV: N, % | 3, 15 | 0, 0 |
| Histological diagnosis | ||
| Squamous cell carcinoma: N, % | 6, 30 | 5, 25 |
| Adenocarcinoma: N, % | 11, 55 | 14, 70 |
| Others: N, % | 3, 15 | 1, 5 |
| Blood parameters | ||
| Total leucocytes/μL | 8.3 103 (1.9 103) | 9.2 103 (2.1 103) |
| Total neutrophils/μL | 5.7 103 (2.1 103) | 6.3 103 (1.7 103) |
| Total lymphocytes/μL | 1.7 103 (650) | 2.1·103 (617) |
| Albumin (g/dL) | 4.4 (0.4) | 4.0 (0.5)¶¶ |
| Total proteins (g/dL) | 7.4 (0.5) | 7.1 (0.6) |
| Fibrinogen (mg/dL) | 485 (99) | 409 (77)¶¶ |
| CRP (mg/dL) | 1.1 (1.1) | 1.7 (1.2) |
| GSV (mm/h) | 20 (7.4) | 30 (16.8)¶ |
| Ceruloplasmin (g/dL) | 26.2 (4.8) | 26.5 (4.8) |
| Body weight loss, kg | ||
| 0, N, % | 18, 90 | 17, 85 |
| 1–4, N, % | 2, 10 | 1, 5 |
| 5–8, N, % | 0, 0 | 2, 10 |
| 9–12, N, % | 0, 0 | 0, 0 |
Continuous variables are presented as mean (standard deviation), while categorical variables are presented as the number of patients in each group and percentage of the total population
Abbreviations: N number, kg kilograms, m meters, BMI body mass index, FEV1 forced expiratory volume in the first second, pred predicted, FVC forced vital capacity, DLco, carbon monoxide transfer, KCO Krogh transfer factor, TNM tumor, nodes, metastasis, CRP C-reactive protein, GSV globular sedimentation velocity, L liter
¶p < 0.05, ¶¶p < 0.01, ¶¶¶p < 0.001 between LC-COPD and LC patients. Comparisons of the clinical and physiological variables between LC-COPD and LC patients were assessed using the Student’s t test. Differences between the study groups in the qualitative variables were assessed using the chi-square test