Table 2.
Univariate analyses and multivariate associations between variables and obstructive coronary artery disease
| Risk factors | Univariate logistic regressiona | Multivariate logistic regressionb | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Age, (per year) | 1.11 | 1.04–1.18 | < 0.01 | 1.02 | 1.00–1.04 | 0.05 |
| Gender (male vs. female) | 2.07 | 1.56–2.69 | < 0.01 | 2.99 | 1.97–4.45 | < 0.01 |
| Hypertension (yes vs. no) | 2.02 | 1.56–2.62 | < 0.01 | 1.72 | 1.17–2.55 | < 0.01 |
| Anemia (yes vs. no) | 1.78 | 1.33–2.37 | < 0.01 | 1.76 | 1.14–2.72 | < 0.01 |
| LVEF (per %) | 0.97 | 0.96–0.99 | < 0.01 | 0.98 | 0.96–1.00 | < 0.01 |
| Hs-CRP (per mmol/l) | 1.04 | 1.01–1.07 | < 0.01 | 1.03 | 1.00–1.05 | 0.07 |
| TC (per 10 mg/dl) | 1.02 | 0.99–1.05 | 0.25 | 1.06 | 1.01–1.11 | 0.03 |
| HDL-C (per mg/dl) | 0.97 | 0.96–0.99 | < 0.01 | 0.98 | 0.96–0.99 | < 0.01 |
OR: odds ratio; CI: confidence interval; LVEF = left ventricular ejection fraction; Hs-CRP = high-sensitivity C-reactive protein; TC: total cholesterol; HDL-C = high-density lipoprotein cholesterol
aUnivariate logistic regression analysis was performed in 1262 patients
bMultivariate logistic regression analysis was performed in 683 patients without missing data of the variables in the final model