Table 3.
Association between CYP1B1 SNPs and RTL
| SNP | Genotype | Short RTL, n (%) | Long RTL, n (%) | OR (95% CI)a | P |
|---|---|---|---|---|---|
| rs9341266 | GG | 58 (27.9) | 64 (29.4) | 1.00 | |
| AG/AA | 150 (72.1) | 154 (70.6) | 1.08 (0.71-1.64) | 0.737 | |
| rs162549 | TT | 44 (21.2) | 48 (22.0) | 1.00 | |
| AT/AA | 164 (78.8) | 170 (78.0) | 1.05 (0.66-1.67) | 0.828 | |
| rs10916 | TT | 35 (16.8) | 54 (24.8) | 1.00 | |
| GT/GG | 173 (83.2) | 164 (75.2) | 1.63 (1.01-2.62) | 0.045 | |
| rs162562 | AA | 60 (28.8) | 66 (30.3) | 1.00 | |
| AC/CC | 148 (71.2) | 152 (69.7) | 1.07 (0.71-1.62) | 0.747 | |
| rs2551188 | CC | 82 (39.4) | 103 (47.2) | 1.00 | |
| CT/TT | 126 (60.6) | 115 (52.8) | 1.38 (0.94-2.02) | 0.104 | |
| rs9341250 | CC | 13 (6.2) | 17 (7.8) | 1.00 | |
| AC/AA | 195 (93.8) | 201 (92.2) | 1.27 (0.60-2.68) | 0.533 | |
| rs1056827 | CC | 67 (32.2) | 69 (31.7) | 1.00 | |
| AC/AA | 141 (67.8) | 149 (68.3) | 0.98 (0.65-1.47) | 0.901 | |
| rs1056836 | CC | 67 (32.2) | 50 (22.9) | ||
| CG/GG | 141 (67.8) | 168 (77.1) | 1.60 (1.04-2.45) | 0.033 |
RTL: Relative telomere length aAdjusted for age and smoking status.