Table 3.

Univariate analysis of factors associated with overall survival of 163 patients with HCC

	OS
	univariate analysis
	HR	95%CI	p-value
Age(>50vs.≤50)	1.15	0.77-1.37	0.47
Gender (male vs. female)	1.61	0.92-2.81	0.10
AFP (≤20 vs.>20)	0.77	0.52-1.14	0.19
HBV (positive vs. negative)	1.03	0.59-1.78	0.93
HCV (positive vs. negative)	0.69	0.22-2.19	0.53
Cirrhosis (yes vs. no)	1.34	0.90-1.99	0.15
Tumor size(cm)(>5 vs. ≤5)	1.19	0.80-1.77	0.39
Tumor encapsulation (none vs. complete)	0.74	0.49-1.10	0.13
Tumor number (multiple vs. single)	0.95	0.51-1.78	0.88
Vascular invasion (yes vs. no)	2.55	1.51-4.31	<0.01
Distant metastasis (positive vs. negative)	0.56	0.21-1.47	0.24
Differentiation (poor-moderate vs. well)	1.74	1.13-2.70	0.01
TNM stage(Ⅱ-Ⅲ-Ⅳvs.Ⅰ)	1.62	1.08-2.44	0.02
SMYD2 expression (positive vs. negative)	2.89	1.87-4.46	<0.01