FIGURE 2.

The impact of NMS and WAS on micturition patterning and fecal output. (A) The number of voids was significantly impacted by NMS and WAS, at the 1-day post-WAS time point, as determined by multiple regression analysis (p < 0.05, R² = 0.318). (B) Total urine output was also significantly impacted by NMS and WAS at the 1-day post-WAS time point (p < 0.05, R² = 0.310), with an additional significant decrease at 8-day post-WAS, compared to baseline, in NMS mice. (C) Fecal output was significantly impacted by NMS (p < 0.05, two-way ANOVA) and a NMS and WAS interaction effect (p < 0.01). Baseline fecal output was significantly higher in NMS mice compared to both naïve baseline output and that of 1-day post-WAS NMS mice. Brackets indicate significant effects: ^∗p < 0.05, ^∗∗p < 0.01; (B) Mann-Whitney U test; (C) Bonferroni posttest. n = 6 per group.