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. Author manuscript; available in PMC: 2018 Jan 17.
Published in final edited form as: Isr J Chem. 2015 Jan 15;55(1):85–95. doi: 10.1002/ijch.201400146

Table 1.

Amino acid sequence of de novo designed 3SCC analogues.[a]

Peptide Sequence
abcdefg abcdefg abcdefg abcdefg abcdefg
CoilSer Ac-E WEALEKK LAALESK LQALEKK LEALEHG −NH2
Baby Ac-G LKALEEK LKALEEK LKALEEK G-NH2
TRI Ac-G LKALEEK LKALEEK LKALEEK LKALEEK G-NH2
Grand Ac-G LKALEEK LKALEEK LKALEEK LKALEEK LKALEEK G-NH2
[a]

Leucine residues at the “a” or “d” positions are mutated to metal-binding residues such as cysteine, penicillamine, or histidine. Mutation of Leu residues to Cys and His at the 9th and 23rd positions, respectively, is designated as TRIL9CL23H.