Skip to main content
. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Breast Cancer Res Treat. 2017 Aug 20;166(3):793–808. doi: 10.1007/s10549-017-4454-7

Table 3.

Breast Swelling

None A little Quite a bit Very Much p-value (little+) p-value (quite a bit+)

POST OP Overall Breast Swelling (N=320) 172 (53.8%) 121 (37.8%) 19 (5.9%) 8 (2.5%)

Vs Arm (N=320) 0.324 0.476
 CMF (Cyclophosphamide, Methotrexate and Fluorouracil) (N=66) 33 (50.0%) 29 (43.9%) 2 (3.0%) 2 (3.0%)
 AC (Doxorubicin and Cyclophosphamide) (N=99) 49 (49.5%) 43 (43.4%) 4 (4.0%) 3 (3.0%)
 Capecitabine (N=155) 90 (58.1%) 49 (31.6%) 13 (8.4%) 3 (1.9%)

Vs Most Extensive Surgery (N=318) 0.981 0.395
 Breast Conserving Surgery (N=143) 77 (53.8%) 56 (39.2%) 6 (4.2%) 4 (2.8%)
 Full Mastectomy (N=175) 94 (53.7%) 64 (36.6%) 13 (7.4%) 4 (2.3%)

Vs Axillary Dissection (N=320) 0.091 0.463
 No (N=65) 41 (63.1%) 20 (30.8%) 2 (3.1%) 2 (3.1%)
 Yes (N=255) 131 (51.4%) 101 (39.6%) 17 (6.7%) 6 (2.4%)

Vs RT (N=300) 0.029 0.507
 No (N=139) 84 (60.4%) 45 (32.4%) 9 (6.5%) 1 (0.7%)
 Yes (N=161) 77 (47.8%) 69 (42.9%) 9 (5.6%) 6 (3.7%)

Vs Number of Nodes Examined (N=313) 0.065 0.562
 0-3 (N=49) 33 (67.3%) 13 (26.5%) 1 (2.0%) 2 (4.1%)
 4-7 (N=53) 31 (58.5%) 19 (35.8%) 1 (1.9%) 2 (3.8%)
 8+ (N=211) 105 (49.8%) 86 (40.8%) 16 (7.6%) 4 (1.9%)

AT 12 MONTHS Overall Breast Swelling (N=257) 225 (87.5%) 25 (9.7%) 5 (1.9%) 2 (0.8%)

Vs Arm (N=257) 0.764 0.452
 CMF (Cyclophosphamide, Methotrexate and Fluorouracil) (N=54) 48 (88.9%) 5 (9.3%) 0 (0%) 1 (1.9%)
 AC (Doxorubicin and Cyclophosphamide) (N=82) 73 (89.0%) 8 (9.8%) 1 (1.2%) 0 (0%)
 Capecitabine (N=121) 104 (86.0%) 12 (9.9%) 4 (3.3%) 1 (0.8%)

Vs Most Extensive Surgery (N=255) 0.329 0.028
 Breast Conserving Surgery (N=115) 98 (85.21%) 11 (9.6%) 5 (4.3%) 1 (0.9%)
 Full Mastectomy (N=140) 125 (89.3%) 14 (10.0%) 0 (0%) 1 (0.7%)

Vs Axillary Dissection (N=257) 0.076 0.691
 No (N=55) 52 (94.5%) 2 (3.6%) 1 (1.8%) 0 (0%)
 Yes (N=202) 173 (85.6%) 23 (11.4%) 4 (2.0%) 2 (1.0%)

Vs RT (N=243) 0.011 0.013
 No (N=109) 102 (93.6%) 7 (6.4%) 0 (0%) 0 (0%)
 Yes (N=134) 111 (82.8%) 16 (11.9%) 5 (3.7%) 2 (1.5%)

Vs Number of Nodes Examined (N=252) 0.097 0.172
 0-3 (N=43) 41 (95.3%) 1 (2.3%) 1 (2.3%) 0 (0%)
 4-7 (N=39) 31 (79.5%) 5 (12.8%) 1 (2.6%) 2 (5.1%)
 8+ (N=170) 148 (87.1%) 19 (11.2%) 3 (1.8%) 0 (0%)

AT 24 MONTHS Overall Breast Swelling (N=240) 217 (90.4%) 21 (8.8%) 1 (0.4%) 1 (0.4%)

Vs Arm (N=240) 0.742 0.363
 CMF (Cyclophosphamide, Methotrexate and Fluorouracil) (N=49) 43 (87.8%) 5 (10.2%) 0 (0%) 1 (2.0%)
 AC (Doxorubicin and Cyclophosphamide) (N=83) 75 (90.4%) 7 (8.4%) 1 (1.2%) 0 (0%)
 Capecitabine (N=108) 99 (91.7%) 9 (8.3%) 0 (0%) 0 (0%)

Vs Most Extensive Surgery (N=238) 0.804 0.201
 Breast Conserving Surgery (N=108) 97 (89.8%) 11 (10.2%) 0 (0%) 0 (0%)
 Full Mastectomy (N=130) 118 (90.8%) 10 (7.7%) 1 (0.8%) 1 (0.8%)

Vs Axillary Dissection (N=240) 0.112 0.475
 No (N=52) 50 (96.2%) 2 (3.8%) 0 (0%) 0 (0%)
 Yes (N=188) 167 (88.8%) 19 (10.1%) 1 (0.5%) 1 (0.5%)

Vs RT (N=226) 0.551 0.919
 No (N=100) 92 (92.0%) 7 (7.0%) 1 (1.0%) 0 (0%)
 Yes (N=126) 113 (89.7%) 12 (9.5%) 0 (0%) 1 (0.8%)

Vs Number of Nodes Examined (N=236) 0.509 0.425
 0-3 (N=41) 39 (95.1%) 2 (4.9%) 0 (0%) 0 (0%)
 4-7 (N=39) 35 (89.7%) 3 (7.7%) 0 (0%) 1 (2.6%)
 8+ (N=156) 139 (89.1%) 16 (10.3%) 1 (0.6%) 0 (0%)