Table 4.
Breast Sensitivity
None | A little | Quite a bit | Very Much | p-value (little+) | p-value (quite a bit+) | ||
---|---|---|---|---|---|---|---|
| |||||||
POST OP | Overall Breast Sensitivity (N=320) | 132 (41.3%) | 146 (45.6%) | 33 (10.3%) | 9 (2.8%) | ||
| |||||||
Vs Arm (N=320) | 0.126 | 0.447 | |||||
CMF (Cyclophosphamide, Methotrexate and Fluorouracil) (N=66) | 20 (30.3%) | 38 (57.6%) | 6 (9.1%) | 2 (3.0%) | |||
AC (Doxorubicin and Cyclophosphamide) (N=99) | 43 (43.4%) | 46 (46.5%) | 9 (9.1%) | 1 (1.0%) | |||
Capecitabine (N=155) | 69 (44.5%) | 62 (40.0%) | 18 (11.6%) | 6 (3.9%) | |||
| |||||||
Vs Most Extensive Surgery (N=318) | 0.176 | 0.530 | |||||
Breast Conserving Surgery (N=143) | 53 (37.1%) | 73 (51.0%) | 14 (9.8%) | 3 (2.1%) | |||
Full Mastectomy (N=175) | 78 (44.6%) | 72 (41.1%) | 19 (10.9%) | 6 (3.4%) | |||
| |||||||
Vs Axillary Dissection (N=320) | 0.081 | 0.062 | |||||
No (N=65) | 33 (50.8%) | 28 (43.1%) | 3 (4.6%) | 1 (1.5%) | |||
Yes (N=255) | 99 (38.8%) | 118 (46.3%) | 30 (11.8%) | 8 (3.1%) | |||
| |||||||
Vs RT (N=300) | 0.019 | 0.051 | |||||
No (N=139) | 67 (48.2%) | 60 (43.2%) | 9 (6.5%) | 3 (2.2%) | |||
Yes (N=161) | 56 (34.8%) | 79 (49.1%) | 22 (13.7%) | 4 (2.5%) | |||
| |||||||
Vs Number of Nodes Examined (N=313) | 0.137 | 0.424 | |||||
0-3 (N=49) | 23 (46.9%) | 21 (42.9%) | 4 (8.2%) | 1 (2.0%) | |||
4-7 (N=53) | 27 (50.9%) | 21 (39.6%) | 3 (5.7%) | 2 (3.8%) | |||
8+ (N=211) | 79 (37.4%) | 100 (47.4%) | 26 (12.3%) | 6 (2.8%) | |||
| |||||||
AT 12 MONTHS | Overall Breast Sensitivity (N=258) | 154 (59.7%) | 90 (34.9%) | 11 (4.3%) | 3 (1.2%) | ||
| |||||||
Vs Arm (N=258) | 0.014 | 0.343 | |||||
CMF (Cyclophosphamide, Methotrexate and Fluorouracil) (N=54) | 24 (44.4%) | 26 (48.2%) | 2 (3.7%) | 2 (3.7%) | |||
AC (Doxorubicin and Cyclophosphamide) (N=82) | 57 (69.5%) | 23 (28.1%) | 2 (2.4%) | 0 (0%) | |||
Capecitabine (N=122) | 73 (59.8%) | 41 (33.6%) | 7 (5.7%) | 1 (0.8%) | |||
| |||||||
Vs Most Extensive Surgery (N=256) | <0.001 | 0.440 | |||||
Breast Conserving Surgery (N=117) | 57 (48.7%) | 55 (47.0%) | 4 (3.4%) | 1 (0.9%) | |||
Full Mastectomy (N=139) | 96 (69.1%) | 34 (24.5%) | 7 (5.0%) | 2 (1.4%) | |||
| |||||||
Vs Axillary Dissection (N=258) | 0.043 | 0.043 | |||||
No (N=56) | 40 (71.4%) | 16 (28.6%) | 0 (0%) | 0 (0%) | |||
Yes (N=202) | 114 (56.4%) | 74 (36.6%) | 11 (5.4%) | 3 (1.5%) | |||
| |||||||
Vs RT (N=244) | <0.001 | 0.643 | |||||
No (N=109) | 84 (77.1%) | 20 (18.3%) | 5 (4.6%) | 0 (0%) | |||
Yes (N=135) | 61 (45.2%) | 66 (48.9%) | 5 (3.7%) | 3 (2.2%) | |||
| |||||||
Vs Number of Nodes Examined (N=253) | 0.725 | 0.201 | |||||
0-3 (N=44) | 27 (61.4%) | 17 (38.6%) | 0 (0%) | 0 (0%) | |||
4-7 (N=39) | 25 (64.1%) | 11 (28.2%) | 1 (2.6%) | 2 (5.1%) | |||
8+ (N=170) | 98 (57.6%) | 61 (35.9%) | 10 (5.9%) | 1 (0.6%) | |||
| |||||||
AT 24 MONTHS | Overall Breast Sensitivity (N=239) | 166 (69.5%) | 62 (25.9%) | 8 (3.3%) | 3 (1.3%) | ||
| |||||||
Vs Arm (N=239) | 0.140 | 0.724 | |||||
CMF (Cyclophosphamide, Methotrexate and Fluorouracil) (N=49) | 32 (65.3%) | 15 (30.6%) | 1 (2.0%) | 1 (2.0%) | |||
AC (Doxorubicin and Cyclophosphamide) (N=82) | 52 (63.4%) | 25 (30.5%) | 3 (3.7%) | 2 (2.4%) | |||
Capecitabine (N=108) | 82 (75.9%) | 22 (20.4%) | 4 (3.7%) | 0 (0%) | |||
| |||||||
Vs Most Extensive Surgery (N=237) | 0.320 | 0.103 | |||||
Breast Conserving Surgery (N=107) | 78 (72.9%) | 27 (25.2%) | 2 (1.9%) | 0 (0%) | |||
Full Mastectomy (N=130) | 87 (66.9%) | 35 (26.9%) | 5 (3.8%) | 3 (2.3%) | |||
| |||||||
Vs Axillary Dissection (N=239) | 0.003 | 0.077 | |||||
No (N=51) | 44 (86.3%) | 7 (13.7%) | 0 (0%) | 0 (0%) | |||
Yes (N=188) | 122 (64.9%) | 55 (29.3%) | 8 (4.3%) | 3 (1.6%) | |||
| |||||||
Vs RT (N=225) | 0.347 | 0.494 | |||||
No (N=100) | 73 (73.0%) | 24 (24.0%) | 3 (3.0%) | 0 (0%) | |||
Yes (N=125) | 84 (67.2%) | 365(28.0%) | 3 (2.4%) | 3 (2.4%) | |||
| |||||||
Vs Number of Nodes Examined (N=235) | 0.293 | 0.756 | |||||
0-3 (N=41) | 29 (70.7%) | 11 (26.8%) | 1 (2.4%) | 0 (0%) | |||
4-7 (N=38) | 30 (79.0%) | 6 (15.8%) | 1 (2.6%) | 1 (2.6%) | |||
8+ (N=156) | 103 (66.0%) | 45 (28.9%) | 6 (3.8%) | 2 (1.3%) |