Table 5.
Breast Pain
None | A little | Quite a bit | Very Much | p-value (little+) | p-value (quite a bit+) | ||
---|---|---|---|---|---|---|---|
| |||||||
POST OP | Overall Breast Pain (N=318) | 130 (40.9%) | 165 (51.9%) | 21 (6.6%) | 2 (0.6%) | ||
| |||||||
Vs Arm (N=318) | 0.364 | 0.863 | |||||
CMF (Cyclophosphamide, Methotrexate and Fluorouracil) (N=65) | 22 (33.8%) | 38 (58.5%) | 4 (6.2%) | 1 (1.5%) | |||
AC (Doxorubicin and Cyclophosphamide) (N=99) | 40 (40.4%) | 53 (53.5%) | 5 (5.1%) | 1 (1.0%) | |||
Capecitabine (N=154) | 68 (44.2%) | 74 (48.1%) | 12 (7.8%) | 0 (0%) | |||
| |||||||
Vs Most Extensive Surgery (N=316) | 0.031 | 0.540 | |||||
Breast Conserving Surgery (N=143) | 49 (34.3%) | 85 (59.4%) | 9 (6.3%) | 0 (0%) | |||
Full Mastectomy (N=173) | 80 (46.2%) | 79 (45.7%) | 12 (6.9%) | 2 (1.2%) | |||
| |||||||
Vs Axillary Dissection (N=318) | 0.210 | 0.147 | |||||
No (N=65) | 31 (47.7%) | 32 (49.2%) | 2 (3.1%) | 0 (0%) | |||
Yes (N=253) | 99 (39.1%) | 133 (52.6%) | 19 (7.5%) | 2 (0.8%) | |||
| |||||||
Vs RT (N=298) | 0.007 | 0.308 | |||||
No (N=137) | 68 (49.6%) | 62 (45.3%) | 6 (4.4%) | 1 (0.7%) | |||
Yes (N=161) | 55 (34.2%) | 93 (57.8%) | 12 (7.5%) | 1 (0.6%) | |||
| |||||||
Vs Number of Nodes Examined (N=311) | 0.846 | 0.038 | |||||
0-3 (N=49) | 21 (42.9%) | 27 (55.1%) | 1 (2.0%) | 0 (0%) | |||
4-7 (N=53) | 23 (43.4%) | 29 (54.7%) | 0 (0%) | 1 (1.9%) | |||
8+ (N=209) | 83 (39.7%) | 105 (50.2%) | 20 (9.6%) | 1 (0.5%) | |||
| |||||||
AT 12 MONTHS | Overall Breast Pain (N=259) | 137 (52.9%) | 109 (42.1%) | 8 (3.1%) | 5 (1.9%) | ||
| |||||||
Vs Arm (N=259) | 0.061 | 0.157 | |||||
CMF (Cyclophosphamide, Methotrexate and Fluorouracil) (N=54) | 21 (38.9%) | 29 (53.7%) | 2 (3.7%) | 2 (3.7%) | |||
AC (Doxorubicin and Cyclophosphamide) (N=82) | 48 (58.5%) | 33 (40.2%) | 0 (0%) | 1 (1.2%) | |||
Capecitabine (N=123) | 68 (55.3%) | 47 (38.2%) | 6 (4.9%) | 2 (1.6%) | |||
| |||||||
Vs Most Extensive Surgery (N=257) | 0.006 | 0.234 | |||||
Breast Conserving Surgery (N=117) | 51 (43.6%) | 58 (49.6%) | 6 (5.1%) | 2 (1.7%) | |||
Full Mastectomy (N=140) | 85 (60.7%) | 50 (35.7%) | 2 (1.4%) | 3 (2.1%) | |||
| |||||||
Vs Axillary Dissection (N=259) | 0.909 | 0.896 | |||||
No (N=56) | 30 (53.6%) | 23 (41.1%) | 1 (1.8%) | 2 (3.6%) | |||
Yes (N=203) | 107 (52.7%) | 86 (42.4%) | 7 (3.4%) | 3 (1.5%) | |||
| |||||||
Vs RT (N=245) | <0.001 | 0.006 | |||||
No (N=109) | 74 (67.9%) | 34 (31.8%) | 1 (0.9%) | 0 (0%) | |||
Yes (N=136) | 55 (40.4%) | 69 (50.7%) | 7 (5.1%) | 5 (3.7%) | |||
| |||||||
Vs Number of Nodes Examined (N=254) | 0.708 | 0.284 | |||||
0-3 (N=44) | 22 (50.0%) | 20 (45.5%) | 1 (2.3%) | 1 (2.2%) | |||
4-7 (N=39) | 23 (59.0%) | 12 (30.8%) | 1 (2.6%) | 3 (7.7%) | |||
8+ (N=171) | 91 (53.2%) | 73 (42.7%) | 6 (3.5%) | 1 (0.6%) | |||
| |||||||
AT 24 MONTHS | Overall Breast Pain (N=240) | 152 (63.3%) | 78 (32.5%) | 8 (3.3%) | 2 (0.8%) | ||
| |||||||
Vs Arm (N=240) | 0.214 | 0.744 | |||||
CMF (Cyclophosphamide, Methotrexate and Fluorouracil) (N=49) | 26 (53.1%) | 20 (40.8%) | 2 (4.1%) | 1 (2.0%) | |||
AC (Doxorubicin and Cyclophosphamide) (N=83) | 53 (63.9%) | 27 (32.5%) | 2 (2.4%) | 1 (1.2%) | |||
Capecitabine (N=108) | 73 (67.6%) | 31 (28.7%) | 4 (3.7%) | 0 (0%) | |||
| |||||||
Vs Most Extensive Surgery (N=238) | 0.281 | 0.100 | |||||
Breast Conserving Surgery (N=108) | 65 (60.2%) | 41 (38.0%) | 2 (1.9%) | 0 (0%) | |||
Full Mastectomy (N=130) | 87 (66.9%) | 35 (26.9%) | 6 (4.6%) | 2 (1.5%) | |||
| |||||||
Vs Axillary Dissection (N=240) | 0.049 | 0.089 | |||||
No (N=52) | 39 (75.0%) | 13 (25.0%) | 0 (0%) | 0 (0%) | |||
Yes (N=188) | 113 (60.1%) | 65 (34.6%) | 8 (4.3%) | 2 (1.1%) | |||
| |||||||
Vs RT (N=226) | 0.032 | 0.990 | |||||
No (N=100) | 71 (71.0%) | 25 (25.0%) | 4 (4.0%) | 0 (0%) | |||
Yes (N=126) | 72 (57.1%) | 49 (38.9%) | 3 (2.4%) | 2 (1.6%) | |||
| |||||||
Vs Number of Nodes Examined (N=236) | 0.265 | 0.334 | |||||
0-3 (N=41) | 24 (58.5%) | 17 (41.5%) | 0 (0%) | 0 (0%) | |||
4-7 (N=39) | 29 (74.4%) | 8 (20.5%) | 1 (2.6%) | 1 (2.6%) | |||
8+ (N=156) | 96 (61.5%) | 52 (33.3%) | 7 (4.5%) | 1 (0.6%) |