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. 2018 Jan 17;13(1):e0190493. doi: 10.1371/journal.pone.0190493

Table 3. Cox proportional hazard model for risk of disease endpoints in all study participants (n = 927).

Number of Incidence, n (%) Unadjusted Model 1 Model 2
normal-range proteinuria abnormal-range proteinuria
(n = 352) (n = 575) HR (95%CI) HR (95%CI) HR (95%CI)
CKD progression 10 (2.8) 213 (37.0) 0.07 (0.03–0.12) 0.08 (0.04–0.14) 0.20 (0.10–0.38)
Cardiovascular events 28 (8.0) 82 (14.3) 0.50 (0.32–0.80) 0.52 (0.33–0.80) 0.73 (0.45–1.19)
All-cause death 18 (5.1) 37 (6.4) 0.72 (0.41–1.26) 0.59 (0.33–1.05) 1.07 (0.56–2.03)

Model 1: Adjusted by age, gender, hypertension, diabetes, and history of CVD. Model 2: Adjusted by Model 1, hemoglobin, serum albumin, and the use of RAAS inhibitor.

Abbreviations: HR, hazard ratio; CI, confidence interval.