Table 3. Cox proportional hazard model for risk of disease endpoints in all study participants (n = 927).
Number of Incidence, n (%) | Unadjusted | Model 1 | Model 2 | ||
---|---|---|---|---|---|
normal-range proteinuria | abnormal-range proteinuria | ||||
(n = 352) | (n = 575) | HR (95%CI) | HR (95%CI) | HR (95%CI) | |
CKD progression | 10 (2.8) | 213 (37.0) | 0.07 (0.03–0.12) | 0.08 (0.04–0.14) | 0.20 (0.10–0.38) |
Cardiovascular events | 28 (8.0) | 82 (14.3) | 0.50 (0.32–0.80) | 0.52 (0.33–0.80) | 0.73 (0.45–1.19) |
All-cause death | 18 (5.1) | 37 (6.4) | 0.72 (0.41–1.26) | 0.59 (0.33–1.05) | 1.07 (0.56–2.03) |
Model 1: Adjusted by age, gender, hypertension, diabetes, and history of CVD. Model 2: Adjusted by Model 1, hemoglobin, serum albumin, and the use of RAAS inhibitor.
Abbreviations: HR, hazard ratio; CI, confidence interval.