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. 2018 Jan 17;13(1):e0190493. doi: 10.1371/journal.pone.0190493

Table 5. Cox proportional hazard model for risk of disease endpoints according to CKD stages (n = 352).

CKD progression Unadjusted Model 1 Model 2
G2 5.18 (0.47–57.13) 4.67 (0.41–53.64) 16.38 (0.62–435.49)
G3a ref ref ref
G3b 1.33 (0.12–14.73) 1.49 (0.13–17.24) 3.81 (0.19–75.40)
G4–G5 4.63 (0.54–39.63) 5.94 (0.63–56.01) 8.21 (0.61–110.28)
Cardiovascular events Unadjusted Model 1 Model 2
G2 0 0 0
G3a ref ref ref
G3b 1.22 (0.45–3.29) 0.67 (0.24–1.91) 0.67 (0.23–1.95)
G4–G5 1.69 (0.63–4.58) 0.70 (0.23–2.14) 0.88 (0.26–2.94)
All-cause death Unadjusted Model 1 Model 2
G2 2.55 (0.16–40.73) 4.81 (0.29–78.90) 5.93 (0.33–105.69)
G3a ref ref ref
G3b 1.35 (0.12–14.91) 0.92 (0.08–10.51) 0.94 (0.08–11.36)
G4–G5 12.86 (1.69–97.84) 7.42 (0.87–63.50) 4.47(0.47–42.21)

Data are presented as hazard ratios (95% confidence intervals).

Model 1: Adjusted by age, gender, hypertension, diabetes, and history of CVD. Model 2, Adjusted by Model 1, hemoglobin, serum albumin, and the use of RAAS inhibitor. Abbreviations: CKD, chronic kidney disease.