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. 2018 Jan 17;13(1):e0190629. doi: 10.1371/journal.pone.0190629

Fig 2. MDR activity factors based on PG and mitoxantrone (MX) accumulation in human PLB and A431 cells.

Fig 2

Effects of the ABCG2 variants on dye extrusion capacity—flow cytometry studies. Panels A. and B.: MDR activity factor (see Methods) calculated by PG accumulation in PLB cells (Panel A) and A431 cells (Panel B), expressing ABCG2 variants. Panels C. and D.: MDR activity factor calculated by MX accumulation in PLB cells (Panel C) and A431 cells (Panel D), expressing ABCG2 variants. +/- SD values are indicated.