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. 2018 Jan 17;13(1):e0190535. doi: 10.1371/journal.pone.0190535

Table 5. Risk of the elevation of liver enzymes in separate age group a using multiple logistic regression model.

Variable (Referent) AST (>45 U/L) ALT (>45 U/L)
Age Category Odds ratio 95% CI Odds ratio 95% CI
10 Sex (Girl) Boy 1.71 1.29–2.25 1.45 1.21–1.75
Frequency of metabolic risk profile b (0) 1 1.65 1.13–2.40 1.67 1.30–2.14
2 2.61 1.78–3.81 2.49 1.92–3.23
3 2.77 1.64–4.69 3.42 2.37–4.92
4 5.03 0.58–43.31 2.07 0.24–17.83
Vegetables/week (No) 1~2 times 0.63 0.42–0.95
3~5 times 0.74 0.49–1.12
Everyday 0.56 0.36–0.87
Meat/week (No) 1~2 times 1.49 1.01–2.19
3~5 times 1.80 1.20–2.70
Everyday 1.13 0.56–2.28
Average amount of sleep/day (<6hours) 6~7 hours 0.88 0.61–1.27
7~8 hours 0.72 0.52–0.99
>8 hours 0.68 0.49–0.95
Self-image of body shape (Normal) Fat 1.12 0.78–1.62 0.95 0.75–1.21
Very fat 1.50 1.04–2.16 1.22 0.95–1.56
≥2 hours/day of computer game (No) Yes 1.34 1.10–1.63
≥2 hours/day of watching TV c (No) Yes 1.59 1.26–2.01 1.36 1.15–1.61
13 or 16 Sex (Girl) Boy 3.64 3.01–4.34 4.56 3.96–5.24
Frequency of metabolic risk profile b (0) 1 1.54 0.95–2.50 2.45 1.58–3.78
2 3.28 2.04–5.30 4.95 3.21–7.63
3 4.31 2.62–7.10 7.35 4.70–11.51
4 7.34 3.83–14.10 9.23 4.97–17.14
Beverage/week (No) 1~2 times 1.10 0.93–1.29
3~5 times 1.29 1.08–1.54
Everyday 1.14 0.82–1.60
Self-image of body shape (Normal) Fat 0.84 0.68–1.02 0.98 0.83–1.15
Very fat 1.58 1.29–1.92 1.75 1.49–2.07
No. of days a week for exercise d (No) 1~2days 0.96 0.84–1.09
3~4days 0.94 0.80–1.09
≥5days 0.69 0.57–0.84
Need help from expert for alcohol or smoking problems d (No) Yes 1.45 1.02–2.06

AST = aspartate transaminase; ALT = alanine transaminase; CI = confidence interval

a age group is distinguished by separate questionnaire according to school year.

b includes obesity by BMI, hypertension, elevated fasting blood glucose and total cholesterol.

c question for elementary school students (7–12 years old)

d question for middle and high school students (13–18years old)